Package: calmate 0.13.0

calmate: Improved Allele-Specific Copy Number of SNP Microarrays for Downstream Segmentation

The CalMaTe method calibrates preprocessed allele-specific copy number estimates (ASCNs) from DNA microarrays by controlling for single-nucleotide polymorphism-specific allelic crosstalk. The resulting ASCNs are on average more accurate, which increases the power of segmentation methods for detecting changes between copy number states in tumor studies including copy neutral loss of heterozygosity. CalMaTe applies to any ASCNs regardless of preprocessing method and microarray technology, e.g. Affymetrix and Illumina.

Authors:Maria Ortiz [aut, ctb], Ander Aramburu [ctb], Henrik Bengtsson [aut, cre, cph], Pierre Neuvial [aut, ctb], Angel Rubio [aut, ctb]

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calmate.pdf |calmate.html
calmate/json (API)
NEWS

# Install 'calmate' in R:
install.packages('calmate', repos = c('https://henrikbengtsson.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/henrikbengtsson/calmate/issues

On CRAN:

acghcopynumbervariantssnpmicroarrayonechanneltwochannelgenetics

2.70 score 1 stars 6 scripts 244 downloads 43 exports 22 dependencies

Last updated 3 years agofrom:e1ce582ed1 (on master). Checks:OK: 7. Indexed: yes.

TargetResultDate
Doc / VignettesOKDec 22 2024
R-4.5-winOKDec 22 2024
R-4.5-linuxOKDec 22 2024
R-4.4-winOKDec 22 2024
R-4.4-macOKDec 22 2024
R-4.3-winOKDec 22 2024
R-4.3-macOKDec 22 2024

Exports:allocateOutputDataSetsallocateOutputDataSets.CalMaTeCalibrationas.character.CalMaTeCalibrationcalmatecalmateByThetaABcalmateByThetaAB.arraycalmateByTotalAndFracBcalmateByTotalAndFracB.arrayCalMaTeCalibrationfindUnitsTodo.CalMaTeCalibrationfitCalMaTefitCalMaTe.matrixfitCalMaTeCNprobesfitCalMaTeCNprobes.matrixfitCalMaTeMediansfitCalMaTeV1fitCalMaTeV2getAsteriskTags.CalMaTeCalibrationgetDataSetsgetDataSets.CalMaTeCalibrationgetFullName.CalMaTeCalibrationgetName.CalMaTeCalibrationgetOutputDataSetsgetOutputDataSets.CalMaTeCalibrationgetParameters.CalMaTeCalibrationgetPath.CalMaTeCalibrationgetReferencesgetReferences.CalMaTeCalibrationgetRootPath.CalMaTeCalibrationgetTags.CalMaTeCalibrationnbrOfFiles.CalMaTeCalibrationprocess.CalMaTeCalibrationsetTags.CalMaTeCalibrationthetaAB2TotalAndFracBthetaAB2TotalAndFracB.arraytotalAndFracB2ThetaABtotalAndFracB2ThetaAB.arraytruncateFracBtruncateFracB.arraytruncateFracB.matrixtruncateThetaABtruncateThetaAB.arraytruncateThetaAB.matrix

Dependencies:aroma.corearoma.lightbase64encBiocManagercodetoolsdigestDNAcopyfutureglobalslistenvMASSmatrixStatsparallellyPSCBSR.cacheR.devicesR.filesetsR.methodsS3R.ooR.rspR.utilsRColorBrewer

Readme and manuals

Help Manual

Help pageTopics
Package calmatecalmate-package calmate
Normalize allele-specific copy numbers (CA,CB)calmateByThetaAB calmateByThetaAB.array
Normalize allele-specific copy numbers (total,fracB)calmateByTotalAndFracB calmateByTotalAndFracB.array
The CalMaTeCalibration classCalMaTeCalibration